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KMID : 0362919890070010037
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1989 Volume.7 No. 1 p.37 ~ p.42
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Squamous Cell Carcinoma of the Supraglottic Larynx Treated with Radiation Therapy
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Park Charn-Il
Kim Kwang-Hyun
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Abstract
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Sixty-six patients with squamous cell carcinoma of the supraglottic larynx received irradiation with curative intent between 1979 and 1985 were retrospectively analysed.
All patients had a minimum follow-up of 4 years. Of the entire group consisting of 73% T3 and T4 lesions and 58% lymph node metastases, a 5-year acturial survival rate was 31.3%. A 5-year acturial survival rates for stage Ⅱ, Ⅲ and IV were 60.7%, 46.7% and 13.5% respectively (p<0.05).
Patients without lymphnode metastases had better survival rate than those with costive lymphnode metastases(54.8% vs 12.2%) (p<0.005). Surgical salvage rate was 4/7 (57%).
Three patients developed distant metastases. Major complications requiring surgery were seen in 11% Radiation therapy alone with surgical salvage was an effective, voice preserving treatment for stage Ⅰ, Ⅱ and selected Ⅲ carcinoma of the supraglottic carcinoma, however planned combined treatment with surgery and radiation therapy is advised for stage Ⅲ and IV carcinoma of the supraglottic larynx with resectable neck disease.
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KEYWORD
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Squamous cell carcinoma, Supraglottic larynx, Radiation therapy, 5-year survival rate
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